Zancong Shen: search on Z-Library

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1

Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with allopurinol in adults with gout: a phase IIa, open-label study

Fleischmann, Roy, Winkle, Peter, Miner, Jeffrey N, Yan, Xiaohong, Hicks, Liz, Valdez, Shakti, Hall, Jesse, Liu, Sha, Shen, Zancong, Gillen, Michael, Hernandez-Illas, Martha

Journal:

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

2

Proteolytic enzymes as a limitation for pulmonary absorption of insulin: in vitro and in vivo investigations

Zancong Shen, Qiang Zhang, Shuli Wei, Tsuneji Nagai

Journal:

International Journal of Pharmaceutics

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

3

Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy adult male subjects

Shen, Zancong, Gillen, Michael, Miner, Jeffrey, Bucci, Gail, Wilson, David, Hall, Jesse

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

4

Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide

Gillen, Michael, Yang, Chun, Wilson, David, Valdez, Shakti, Lee, Caroline, Kerr, Bradley, Shen, Zancong

Journal:

Clinical Pharmacology in Drug Development

Year:

2017

Language:

english

File:

PDF, 289 KB

english, 2017

5

Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

Gillen, Michael, Valdez, Shakti, Zhou, Dongmei, Kerr, Bradley, Lee, Caroline A., Shen, Zancong

Journal:

Drug Design Development and Therapy

Year:

2016

Language:

english

File:

PDF, 827 KB

english, 2016

6

Intravesical Treatments of Bladder Cancer: Review

Zancong Shen, Tong Shen, M. Guillaume Wientjes, Michael A. O’Donnell, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 214 KB

english, 2008

7

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

Miner, Jeffrey N., Tan, Philip K., Hyndman, David, Liu, Sha, Iverson, Cory, Nanavati, Payal, Hagerty, David T., Manhard, Kimberly, Shen, Zancong, Girardet, Jean-Luc, Yeh, Li-Tain, Terkeltaub, Robert,

Journal:

Arthritis Research & Therapy

Year:

2016

Language:

english

File:

PDF, 226 KB

english, 2016

8

Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans

Lee, Caroline A., Yang, Chun, Shah, Vishal, Shen, Zancong, Wilson, David M, Ostertag, Traci M., Hall, Jesse, Girardet, Jean-Luc, Gillen, Michael

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 541 KB

english, 2018

9

Predictive Models of Diffusive Nanoparticle Transport in 3-Dimensional Tumor Cell Spheroids

Gao, Yue, Li, Mingguang, Chen, Bin, Shen, Zancong, Guo, Peng, Wientjes, M. Guillaume, Au, Jessie L.-S.

Journal:

The AAPS Journal

Year:

2013

Language:

english

File:

PDF, 587 KB

english, 2013

10

Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor

Shen, Zancong, Lee, Caroline A., Valdez, Shakti, Yang, Xiaojuan, Wilson, David M., Flanagan, Talia, Gillen, Michael

Journal:

Clinical Pharmacology in Drug Development

Year:

2019

File:

PDF, 660 KB

2019

11

Low-frequency ultrasound as a transcutaneous immunization adjuvant

Ahmet Tezel, Sumit Paliwal, Zancong Shen, Samir Mitragotri

Journal:

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

12

In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters

Shen, Zancong, Yeh, Li-Tain, Wallach, Kathleen, Zhu, Nanqun, Kerr, Brad, Gillen, Michael

Journal:

Clinical Drug Investigation

Year:

2016

Language:

english

File:

PDF, 509 KB

english, 2016

13

Safety and efficacy of verinurad, a selective URAT1 inhibitor, for the treatment of patients with gout and/or asymptomatic hyperuricemia in the United States and Japan: Findings from two Phase II trials

Fitz-Patrick, David, Roberson, Kent, Niwa, Kiyoshi, Fujimura, Takabumi, Mori, Koji, Hall, Jesse, Yan, Xiaohong, Shen, Zancong, Liu, Sha, Ito, Yasushi, Baumgartner, Scott

Journal:

Modern Rheumatology

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

14

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

Miner, Jeffrey N., Tan, Philip K., Hyndman, David, Liu, Sha, Iverson, Cory, Nanavati, Payal, Hagerty, David T., Manhard, Kimberly, Shen, Zancong, Girardet, Jean-Luc, Yeh, Li-Tain, Terkeltaub, Robert,

Journal:

Arthritis Research & Therapy

Year:

2016

Language:

english

File:

PDF, 991 KB

english, 2016

15

Paclitaxel Tumor-Priming Enhances siRNA Delivery and Transfection in 3-Dimensional Tumor Cultures

Wong, Ho Lun, Shen, Zancong, Lu, Ze, Wientjes, M. Guillaume, Au, Jessie L.-S.

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 3.48 MB

english, 2011

16

Lanthanides’ enhancing absorption of insulin and reduction of blood glucose of rat by pulmonary administration

Yi Cheng, Zancong Shen, Qiang Zhang, Rongchang Li, Shuli Wei, Kui Wang

Journal:

Chinese Science Bulletin

Year:

2000

Language:

english

File:

PDF, 447 KB

english, 2000

17

Metabolism and Disposition of Lesinurad, a Uric Acid Reabsorption Inhibitor, in Humans

Shah, Vishal, Yang, Chun, Shen, Zancong, Kerr, Bradley M., Tieu, Kathy, Wilson, David M., Hall, Jesse, Gillen, Michael, Lee, Caroline A.

Journal:

Year:

2018

Language:

english

File:

PDF, 994 KB

english, 2018

18

Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Administration of Verinurad and Febuxostat in Healthy Male Volunteers

Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong

Journal:

Clinical Pharmacology in Drug Development

Year:

2018

Language:

english

File:

PDF, 257 KB

english, 2018

19

Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study

Shen, Zancong, Gillen, Michael, Tieu, Kathy, Nguyen, Mai, Harmon, Erin, Wilson, David M, Kerr, Bradley, Lee, Caroline A

Journal:

Drug Design Development and Therapy

Year:

2016

Language:

english

File:

PDF, 831 KB

english, 2016

20

Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers

Shen, Zancong, Lee, Caroline A., Wallach, Kathleen, Valdez, Shakti, Wilson, David M., Kerr, Bradley, Gillen, Michael

Journal:

Clinical Pharmacology in Drug Development

Year:

2019

File:

PDF, 456 KB

2019

21

Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy Japanese and non-Asian male subjects

Hall, Jesse, Gillen, Michael, Liu, Sha, Miner, Jeffrey N, Valdez, Shakti, Shen, Zancong, Lee, Caroline

Journal:

Drug Design Development and Therapy

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

22

Oral delivery of macromolecules using intestinal patches: applications for insulin delivery

Kathryn Whitehead, Zancong Shen, Samir Mitragotri

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 382 KB

english, 2004

23

Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

Shen, Zancong, Rowlings, Colin, Kerr, Brad, Hingorani, Vijay, Manhard, Kimberly, Quart, Barry, Yeh, Li-Tain, Storgard, Chris

Journal:

Drug Design Development and Therapy

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

24

Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor

Shen, Zancong, Lee, Caroline A., Valdez, Shakti, Yang, Xiaojuan, Wilson, David M., Flanagan, Talia, Gillen, Michael

Journal:

Clinical Pharmacology in Drug Development

Year:

2019

Language:

english

File:

PDF, 660 KB

english, 2019

25

Intestinal Patches for Oral Drug Delivery

Zancong Shen, Samir Mitragotri

Journal:

Pharmaceutical Research

Year:

2002

Language:

english

File:

PDF, 332 KB

english, 2002

26

Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Multiple Dose Administration of Verinurad (RDEA3170) and Allopurinol in Adult Male Subjects With Gout

Kankam, Martin, Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong, Lee, Caroline, Liu, Sha, Miner, Jeffrey N., Walker, Susan, Clauson, Vicki, Wilson, David, Nguyen, Mai

Journal:

Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 389 KB

english, 2018

27

Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study

Shiramoto, Masanari, Liu, Sha, Shen, Zancong, Yan, Xiaohong, Yamamoto, Amy, Gillen, Michael, Ito, Yasushi, Hall, Jesse

Journal:

Year:

2018

Language:

english

File:

PDF, 518 KB

english, 2018

28

Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats

Qiang Zhang, Zancong Shen, Tsuneji Nagai

Journal:

International Journal of Pharmaceutics

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

29

The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout

Baumgartner, Scott, Yeh, Li-Tain, Shen, Zancong, Kerr, Bradley, Manhard, Kimberly, Quart, Barry

Journal:

Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 486 KB

english, 2018

30

Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Verinurad, a Selective Uric Acid Reabsorption Inhibitor

Smith, William B., Hall, Jesse, Berg, Jolene K., Kazimir, Michal, Yamamoto, Amy, Walker, Susan, Lee, Caroline A., Shen, Zancong, Wilson, David M., Zhou, Dongmei, Gillen, Michael, Marbury, Thomas C.

Journal:

Clinical Drug Investigation

Year:

2018

Language:

english

File:

PDF, 595 KB

english, 2018

31

CHARACTERIZATION OF STEREOSELECTIVE METABOLISM, INHIBITORY EFFECT ON URIC ACID UPTAKE TRANSPORTERS, AND PHARMACOKINETICS OFLESINURAD ATROPISOMERS

Yang, Chun, Zhou, Dongmei, Shen, Zancong, Wilson, David M, Renner, Matthew, Miner, Jeffrey N, Girardet, Jean-Luc, Lee, Caroline A

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 562 KB

english, 2018

32

Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers

Shen, Zancong, Lee, Caroline A., Wallach, Kathleen, Valdez, Shakti, Wilson, David M., Kerr, Bradley, Gillen, Michael

Journal:

Clinical Pharmacology in Drug Development

Year:

2019

Language:

english

File:

PDF, 456 KB

english, 2019

33

Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment

Shen, Zancong, Tieu, Kathy, Wilson, David, Bucci, Gail, Gillen, Michael, Lee, Caroline, Kerr, Bradley

Journal:

Clinical Pharmacology in Drug Development

Year:

2017

Language:

english

File:

PDF, 306 KB

english, 2017

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